Crouch: i like to recommend the default bind (C). If you're a CS player CTRL may come more naturally, but doing so will overlap awkwardly with many other binds that use CTRL as a modifier. I suppose you'll always make C the modifier for these binds.
Leaning: Some say switching Q and E makes leaning and strafing easier, since you'll use opposite fingers to lean and move within the same direction. I personally haven't tried this but it might be worth considering.
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